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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3713 | BAY-876 | transporter | |
BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol... | |||
T9558 | KL-11743 | transporter | |
KL-11743 specifically blocks glucose metabolism, triggering an acute collapse in NADH pools and a striking accumulation of aspartate, indicating a dramatic shift toward oxidative phosphorylation in the mitochondria. | |||
T2363 | STF-31 | transporter , Autophagy | |
STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM. | |||
T7018 | WZB117 | transporter | |
WZB117 is a Glucose Transporter 1 (GLUT1) inhibitor. when IC50 of WZB117 approximate 10 μM, it inhibits lung cancer A549 cells and breast cancer MCF7 cells proliferation. | |||
T8616 | Fasentin | N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide | transporter |
Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1. | |||
T8732 | CTPI-2 | Others , Mitochondrial Metabolism | |
CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 ha... | |||
T4182 | Lavendustin B | Tyrosinase , transporter , HIV Protease | |
Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75). | |||
TN1118 | Tormentic acid | Immunology/Inflammation related | |
Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties, | |||
T4S1545 | Licarin B | (-)-Licarin B,Licarine B | transporter , Antibacterial , PPAR |
1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity. | |||
T2924 | Phloretin | Dihydronaringenin,NSC 407292,RJC 02792 | SGLT , transporter , Endogenous Metabolite |
Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leav... | |||
T6S0117 | Avicularin | Fenicularin | ERK |
Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX... | |||
TN1033 | Sennidin A | HCV Protease , transporter , Akt , PI3K | |
Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM. | |||
TN1034 | Sennidin B | HCV Protease , transporter , Akt , PI3K | |
Sennidin B stimulates glucose incorporation in rat adipocytes. | |||
T2755 | Rhoifolin | Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside | Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy |
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves. | |||
T9590 | T-1095 | SGLT , transporter | |
T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2). | |||
T38843 | Enavogliflozin | DWP-16001 | SGLT |
Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor. | |||
T3547 | Sotagliflozin | LX-4211,LP-802034 | SGLT |
Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potential antihyperglycemic activity. | |||
T22317 | DRB18 | transporter | |
DRB18 is a highly effective pan-class inhibitor of glucose transporter proteins (GLUT). It significantly modulates energy-related metabolism in A549 cells by inducing alterations in the abundance of metabolites associate... | |||
T1782 | Canagliflozin | JNJ 24831754ZAE,JNJ 28431754AAA,TA 7284,JNJ 28431754 | SGLT |
Canagliflozin (JNJ 28431754AAA), a sodium-glucose transporter 2( SGLT2) and P-Glycoprotein inhibitor, is used in type 2 diabetes. | |||
T33412 | MitoPQ | MitoParaquat | Glucokinase , transporter |
MitoPQ (MitoParaquat) is a mitochondria-targeted small molecule compound that selectively enhances mitochondrial superoxide and hydrogen peroxide levels and inhibits insulin-stimulated glucose uptake and translocation of... |